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Emerging roles of podoplanin in vascular development and homeostasis
null
《医学前沿(英文)》 2015年 第9卷 第4期 页码 421-430 doi: 10.1007/s11684-015-0424-9
Podoplanin (PDPN) is a mucin-type O-glycoprotein expressed in diverse cell types, such as lymphatic endothelial cells (LECs) in the vascular system and fibroblastic reticular cells (FRCs) in lymph nodes. PDPN on LECs or FRCs activates CLEC-2 in platelets, triggering platelet activation and/or aggregation through downstream signaling events, including activation of Syk kinase. This mechanism is required to initiate and maintain separation of blood and lymphatic vessels and to stabilize high endothelial venule integrity within lymph nodes. In the vascular system, normal expression of PDPN at the LEC surface requires transcriptional activation of Pdpn by Prox1 and modification of PDPN with core 1-derived O-glycans. This review provides a comprehensive overview of the roles of PDPN in vascular development and lymphoid organ maintenance and discusses the mechanisms that regulate PDPN expression related to its function.
关键词: podoplanin CLEC-2 Prox1 O-glycosylation lymphatic vascular development and maintenance lymphoid organ homeostasis
通过<i> B i>位Ta置换对<i> AB i> O4型EuNbO4的热学和力学性质进行优化 Article
陈琳, 冯晶
《工程(英文)》 2020年 第6卷 第2期 页码 177-184 doi: 10.1016/j.eng.2019.12.006
铁弹性的ABO4型RETaO4陶瓷和RENbO4陶瓷(RE表示稀土)是具有潜在应用价值的热障涂层(TBC)材料,
H2 对Pt-Ba-Ce /γ-Al2O3 催化剂NO<i>xi> 存储和还原机理的影响研究 Article
王攀, 裔静, 孙川, 罗鹏, 雷利利
《工程(英文)》 2019年 第5卷 第3期 页码 568-575 doi: 10.1016/j.eng.2019.02.005
本研究采用浸渍法制备了Pt-Ba-Ce/γ-Al2O3催化剂,利用实验评价了H2 对NSR(NOx storage and reduction)催化剂存储和还原机理的影响,并采用综合表征技术研究了Pt-Ba-Ce /γ-Al2O3x、CeO2 和BaCO3 峰很好地分散在γ-Al2O<
Tian Jiang, Yuhui Hou, Tengjiang Zhang, Xudong Feng, Chun Li
《化学科学与工程前沿(英文)》 2019年 第13卷 第3期 页码 554-562 doi: 10.1007/s11705-019-1834-z
关键词: β-glucuronidase enzyme-inorganic hybrid nanoflower biotransformation glycyrrhizin glycyrrtinic acid 3-O-mono-β-D-glucuronide
><i>In situi> growth of phosphorized ZIF-67-derived amorphous CoP/Cu2O@CF electrocatalyst
《化学科学与工程前沿(英文)》 2023年 第17卷 第10期 页码 1430-1439 doi: 10.1007/s11705-023-2320-1
Anefficient data layout scheme for better I/O balancing inRAID-6 storage systems
Ping XIE,Jian-zhong HUANG,Er-wei DAI,Qiang CAO,Chang-sheng XIE
《信息与电子工程前沿(英文)》 2015年 第16卷 第5期 页码 335-345 doi: 10.1631/FITEE.1400362
关键词: RAID-6 Data availability High performance I/O balancing
针对I/O密集型应用的新型非易失存储系统 None
Wen-bing HAN, Xiao-gang CHEN, Shun-fen LI, Ge-zi LI, Zhi-tang SONG, Da-gang LI, Shi-yan CHEN
《信息与电子工程前沿(英文)》 2018年 第19卷 第10期 页码 1291-1302 doi: 10.1631/FITEE.1700061
Functional characterization of caffeic acid
Fengyan WU, Zhenying WU, Aiguo YANG, Shanshan JIANG, Zeng-Yu WANG, Chunxiang FU
《农业科学与工程前沿(英文)》 2018年 第5卷 第1期 页码 98-107 doi: 10.15302/J-FASE-2017198
关键词: biofuel crop caffeic acid O-methyltransferase forage lignin Panicum virgatum switchgrass transgenic plant
Hydroxyl radical intensified Cu
Wenyue Li, Min Chen, Zhaoxiang Zhong, Ming Zhou, Weihong Xing
《环境科学与工程前沿(英文)》 2020年 第14卷 第6期 doi: 10.1007/s11783-020-1281-6
关键词: Ceramic membrane reactor N N-dimethylacetamide Fenton process Cu2O Wastewater treatment
流感与COVID-19患者的免疫球蛋白G糖基化差异 Article
Hadžibegović, Barbara Radovani, Ivana Jurin, Lovorka Đerek, Eva Huljev, Alemka Markotić, Ivica Lukšić, Irena Trbojević-Akmačić, Gordan Lauc, Ivan Gudelj, Rok Čivljak
《工程(英文)》 2023年 第26卷 第7期 页码 54-62 doi: 10.1016/j.eng.2022.08.007
The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances. These glycans impact the antibody stability, half-life, secretion, immunogenicity, and effector functions. Therefore, in this study, we analyzed and compared the total IgG glycome—at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))—of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls. Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased. On the other hand, IgG galactosylation remained stable in influenza patients and COVID-19 survivors. IgG glycosylation in influenza patients was more time-dependent: In the first seven days of the disease, sialylation increased and fucosylation and bisecting GlcNAc decreased; in the next 21 days, sialylation decreased and fucosylation increased (while bisecting GlcNAc remained stable). The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.
《环境科学与工程前沿(英文)》 2022年 第16卷 第10期 doi: 10.1007/s11684-022-1565-0
● Cu addition enhances CH3OH oxidation and alleviates its inhibitory effect on SCR.
关键词: Copper modification Sb-CeZr2Ox catalyst NOx Methanol Simultaneous removal
Xiaoliu LI, Xinhao YAN, Zhiwei LI, Hua CHEN, Pingzhu ZHANG,
《化学科学与工程前沿(英文)》 2010年 第4卷 第3期 页码 342-347 doi: 10.1007/s11705-009-0279-1
关键词: photoelectron spectroscopy adsorption-desorption glycosylation deactivated diffraction
Mingxin Dong, Jun Wang, Jinxin Zhu, Jianqiang Wang, Wulin Wang, Meiqing Shen
《环境科学与工程前沿(英文)》 2017年 第11卷 第6期 doi: 10.1007/s11783-017-0976-9
关键词: NOx storage reduction Pt/BaO/Al2O3 Pd doping N2O formation Optimization
CFD evaluation of pressure drop across a 3-D filter housing for industrial gas turbine plants
Fidelis I. ABAM,Samuel O. EFFIOM,Olayinka S. OHUNAKIN
《能源前沿(英文)》 2016年 第10卷 第2期 页码 192-202 doi: 10.1007/s11708-016-0406-x
关键词: computational fluid dynamics (CFD) pressure drop flow distribution filter housing gas turbine
戚隆宁,张哲,黄少珉
《中国工程科学》 2008年 第10卷 第2期 页码 60-65
减少I/O设备功耗已越来越被嵌入式系统设计者所关注。传统动态功耗管理(DPM)策略在实 际的多任务环境下无法得到预期的节能效果。该 策略通过分析任务的调用和堆栈信息来预测任务对I/O设备的访问模式,并采用多请求源(MSR)模型进行多任务的联合预测。然后根据预测结果分组统计,采用超时技术决策。
标题 作者 时间 类型 操作
hybrid nanoflower through protein-inorganic self-assembly, and its application in glycyrrhetinic acid 3-O-mono-β-D-glucuronide
Tian Jiang, Yuhui Hou, Tengjiang Zhang, Xudong Feng, Chun Li
期刊论文
Anefficient data layout scheme for better I/O balancing inRAID-6 storage systems
Ping XIE,Jian-zhong HUANG,Er-wei DAI,Qiang CAO,Chang-sheng XIE
期刊论文
针对I/O密集型应用的新型非易失存储系统
Wen-bing HAN, Xiao-gang CHEN, Shun-fen LI, Ge-zi LI, Zhi-tang SONG, Da-gang LI, Shi-yan CHEN
期刊论文
Functional characterization of caffeic acid
Fengyan WU, Zhenying WU, Aiguo YANG, Shanshan JIANG, Zeng-Yu WANG, Chunxiang FU
期刊论文
流感与COVID-19患者的免疫球蛋白G糖基化差异
Hadžibegović, Barbara Radovani, Ivana Jurin, Lovorka Đerek, Eva Huljev, Alemka Markotić, Ivica Lukšić, Irena Trbojević-Akmačić, Gordan Lauc, Ivan Gudelj, Rok Čivljak
期刊论文
Tailoring the simultaneous abatement of methanol and NO on Sb-Ce-Zr catalysts via copper modification
期刊论文
Catalysis and deactivation of montmorillonite K10 in the aryl O -glycosylation of glycosyl trichloroacetoimidates
Xiaoliu LI, Xinhao YAN, Zhiwei LI, Hua CHEN, Pingzhu ZHANG,
期刊论文
Effects of Pd doping on N
Mingxin Dong, Jun Wang, Jinxin Zhu, Jianqiang Wang, Wulin Wang, Meiqing Shen
期刊论文
CFD evaluation of pressure drop across a 3-D filter housing for industrial gas turbine plants
Fidelis I. ABAM,Samuel O. EFFIOM,Olayinka S. OHUNAKIN
期刊论文